JAX vs SF -- Sunday, September 28, 2025 - 3:05 PM CST
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NFL NFL Predictions:
Jacksonville Jaguars vs San Francisco 49ers at Levi's Stadium in Santa Clara.
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Jacksonville Jaguars vs San Francisco 49ers
Game starts at Sunday, September 28, 2025 - 3:05 PM CST, with trading being allowed until Sunday, September 28, 2025 - 2:53 PM CST
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WHO WILL WIN?
Jacksonville Jaguars vs San Francisco 49ers
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NFL 2025: Week 4 - Predict Winner: Jacksonville Jaguars or San Francisco 49ers
Odds say San Francisco 49ers:
67.2%