MLB Predictions:

Chicago Cubs vs San Diego Padres at PETCO Park in San Diego.

VS

Chicago Cubs vs San Diego Padres

Game starts at Wednesday, April 29, 2026 - 3:10 PM CST, with trading being allowed until Wednesday, April 29, 2026 - 2:58 PM CST

Make your free predictions & come back to see if you've won!

The new MLB season is here! The 2026 MLB season begins with a special matchup between the San Francisco Giants and New York Yankees on March 25, followed by Opening Day on March 26. A major rule change introduces a ball-strike challenge system, giving teams two challenges per game. The 96th All-Star Game is in Philadelphia on July 14, and the regular season runs through Sept. 27.

WHO WILL WIN?

Chicago Cubs vs San Diego Padres